{"id":177504,"date":"2023-03-29T11:43:29","date_gmt":"2023-03-29T10:43:29","guid":{"rendered":"https:\/\/www.directhealthcaregroup.com\/?page_id=177504"},"modified":"2023-05-17T06:32:40","modified_gmt":"2023-05-17T05:32:40","slug":"177504-2","status":"publish","type":"page","link":"https:\/\/www.directhealthcaregroup.com\/da\/viden-og-evidens\/177504-2\/","title":{"rendered":"S\u00f8vn: kroppens vigtigste medicin"},"content":{"rendered":"\n

<\/h1>\n\n\n\n

Alle mennesker sover, og de fleste opfatter s\u00f8vn som en selvf\u00f8lge. Alligevel er det de f\u00e6rreste, der ved, hvad s\u00f8vnen g\u00f8r ved vores krop. Men forskere har gennem de seneste \u00e5r bevist, at s\u00f8vn er en gratis og bivirkningsfri medicin, der g\u00f8r os \u201dfit for fight\u201d og holder sygdomme fra livet.<\/p>\n\n\n\n

11. februar 2020<\/p>\n\n\n\n

Af: Ergoterapeut, Pia Beck<\/p>\n\n\n\n

Kroppens v\u00e6rn mod giftstoffer<\/strong><\/h2>\n\n\n\n

Menneskets krop bruger energi i de v\u00e5gne timer. N\u00e5r energien forbr\u00e6ndes, ophobes der et signalstof ved navn Adenosin, der d\u00e6mper hjernens evne til at sende nervesignaler. Koncentrationen af Adenosin stiger i takt med en stigende hjerneaktivitet i l\u00f8bet af dagen. Jo h\u00f8jere niveau af Adenosin der er i hjernen, des s\u00f8vnigere bliver vi.<\/p>\n\n\n\n

I l\u00f8bet af aftenen bliver koncentrationen af Adenosin s\u00e5 h\u00f8j, at hjernen gradvist k\u00f8rer langsommere, og efterh\u00e5nden som dagen g\u00e5r p\u00e5 h\u00e6ld, begynder vi at f\u00f8le os tr\u00e6tte. \u00d8jenl\u00e5gene bliver tunge, og s\u00f8vnen presser sig p\u00e5.<\/p>\n\n\n\n

Forskere har bevist, at en god nattes\u00f8vn, og specielt den dybe s\u00f8vn, nulstiller niveauet af Adenosin og andre giftstoffer, s\u00e5 vi er friske og klar til en ny dag. F\u00e5r vi ikke sovet tilstr\u00e6kkeligt, vil der v\u00e6re en \u00f8get m\u00e6ngde af giftstoffer i vores hjerne, og vi vil derfor hurtigere f\u00f8le os tr\u00e6tte og uoplagte n\u00e6ste dag. Hertil kommer at manglen p\u00e5 s\u00f8vn ogs\u00e5 er forbundet til udviklingen af kroniske sygdomme<\/a> s\u00e5som diabetes, hjerte-kar-sygdomme, depression og overv\u00e6gt. Derfor har vi alle behov for en god nattes\u00f8vn.<\/p>\n\n\n\n


L\u00e6s ogs\u00e5:<\/strong> Fire r\u00e5d til god s\u00f8vn<\/a><\/p>\n\n\n\n

Hjernen vaskes ren i nattens mulm og m\u00f8rke<\/strong><\/h2>\n\n\n\n

Det interessante sp\u00f8rgsm\u00e5l er s\u00e5, hvordan niveauet af Adenosin nulstilles. Det har et forskerhold, med Maiken Nedergaard i spidsen, unders\u00f8gt i 2012, hvor de som de f\u00f8rste beskrev hjernens reng\u00f8ringssystem.<\/p>\n\n\n\n

Systemet fungerer delvist som det lymfatiske system i resten af kroppen, og holdet navngav det derfor det glymphatiske system (\u2019g\u2019et st\u00e5r for gliaceller, der driver v\u00e6sketransporten). De kunne konstatere, at det glymphatiske system var et hidtil ukendt system til v\u00e6sketransport i hjernen, der best\u00e5r af et mikroskopisk net i hjerneskallen, der skyller hjernen igennem.<\/p>\n\n\n\n

Nogle aspekter af det glymphatiske system var beskrevet af tidligere forskning, men der var ikke nogen, der f\u00f8r havde beskrevet at v\u00e6skestr\u00f8mme i hjernen, fjerner affaldsstoffer, og at det prim\u00e6rt sker, mens vi sover.<\/p>\n\n\n\n

Selvom forskning i det glymphatiske system fortsat er ny, st\u00f8tter det op omkring, den viden vi allerede har om \u200b\u200bden biologiske n\u00f8dvendighed af s\u00f8vn. Resultaterne peger nemlig p\u00e5, at affaldsstoffer vil hobe sig op i hjernen og nedbryde hjerneceller, uden regelm\u00e6ssig s\u00f8vn.
<\/p>\n\n\n\n

Den menneskelige vaskemaskine<\/strong><\/h2>\n\n\n\n

I deres fors\u00f8g p\u00e5 sovende mus kunne forskerne se, at den plads (det interstitiale rum), der omgiver vores nerveceller, \u00f8ges med 60 % under s\u00f8vnen, fordi hjernens st\u00f8tteceller (ogs\u00e5 kaldet gliaceller) midlertidigt skrumper. Denne \u00f8gede plads giver mulighed for en hurtigere udveksling af interstitial v\u00e6ske med rygmarvsv\u00e6ske. Denne udveksling ben\u00e6vnes den glymphatiske clearence<\/em>, eller hjernens vaskemaskine. Det er herigennem at affaldsstofferne udskilles via nyrerne eller til nedbrydning i leveren.<\/p>\n\n\n\n

Med kendskab til det glymphatiske system, eller den menneskelige vaskemaskine, giver det god mening, at vi, efter en nat med manglende s\u00f8vn, bliver tr\u00e6tte, da hjernen ikke er blevet vasket tilstr\u00e6kkeligt ren. Men selvom vi nu har f\u00e5et mere viden om, hvordan affaldsstoffer fra hjernen vaskes v\u00e6k under s\u00f8vn, mangler der if\u00f8lge Maiken Nedergaard stadigv\u00e6k nogle vigtige detaljer om, hvordan det glymphatiske system egentlig ser ud.<\/p>\n\n\n\n

L\u00e6s ogs\u00e5:<\/strong> Lejring og respiration<\/a><\/p>\n\n\n\n

Det gennemsigtige kranie<\/strong><\/h2>\n\n\n\n

Det har indtil for nylig ikke v\u00e6ret muligt, med de scanningsteknikker forskerne har haft, at aflure pr\u00e6cist, hvordan hjernens vaskesystem fungerer. Men for et \u00e5rs tid siden kom der en ny scanningsteknik, der kan g\u00f8re kraniet gennemsigtigt, og som g\u00f8r det muligt at se r\u00f8rf\u00f8ringen i det glymphatiske system. Den nye scanningsteknik er blevet d\u00f8bt vDISCO, og er udviklet af en tyrkisk neuroforsker ved navn Ali Ert\u00fcrk.<\/p>\n\n\n\n

Fra musefors\u00f8g kan man se, at der i en pattedyrshjerne er lymfekar, og at disse lymfekar forbinder hjernen direkte med kraniet. Disse Lymfekar er s\u00e5 mikroskopiske, at de aldrig ville v\u00e6re opdaget, hvis man tog musehjernen ud af kraniet. Og p\u00e5 samme m\u00e5de vil det v\u00e6re hos mennesker.<\/p>\n\n\n\n

Denne nye teknik giver sandsynligvis forskerne muligheden for at f\u00e5 svar p\u00e5 en lang r\u00e6kke interessante sp\u00f8rgsm\u00e5l s\u00e5som; Hvordan ser det glymphatiske system ud hos mennesker med Alzheimers sammenlignet med raske j\u00e6vnaldrende? Hvad sker der med systemet, n\u00e5r man sl\u00e5r sit hoved? Og kunne det t\u00e6nkes, at alvorlig depression p\u00e5virker dette r\u00f8rf\u00f8ringssystem?<\/p>\n\n\n\n

Svarene p\u00e5 disse sp\u00f8rgsm\u00e5l har vi ikke endnu. Men der er ingen tvivl om, at den gode, dybe s\u00f8vn er afg\u00f8rende for vores velbefindende og helbredstilstand. Derfor er det vigtigt allerede nu at have stort fokus p\u00e5 at sikre borgere og patienter en god s\u00f8vnkvalitet.<\/p>\n","protected":false},"excerpt":{"rendered":"

Alle mennesker sover, og de fleste opfatter s\u00f8vn som en selvf\u00f8lge. Alligevel er det de f\u00e6rreste, der ved, hvad s\u00f8vnen g\u00f8r ved vores krop. Men forskere har gennem de seneste \u00e5r bevist, at s\u00f8vn er en gratis og bivirkningsfri medicin, der g\u00f8r os \u201dfit for fight\u201d og holder sygdomme fra livet. 11. februar 2020 Af: … Continued<\/a><\/p>\n","protected":false},"author":40,"featured_media":177518,"parent":174696,"menu_order":29,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-177504","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nS\u00f8vn: kroppens vigtigste medicin | DHG<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.directhealthcaregroup.com\/da\/viden-og-evidens\/177504-2\/\" \/>\n<meta property=\"og:locale\" content=\"da_DK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"S\u00f8vn: kroppens vigtigste medicin | DHG\" \/>\n<meta property=\"og:description\" content=\"Alle mennesker sover, og de fleste opfatter s\u00f8vn som en selvf\u00f8lge. 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